NUMERICAL INVESTIGATION OF PHOTONIC CRYSTAL FIBER BASED PLASMONIC BIOSENSOR FOR EARLY DETETCTION OF CANCER

Abstract

This work proposes Surface Plasmon Resonance based Photonic Crystal Fiber for cancer detection. Both the proposed sensors are refractive index sensors that is highly sensitive towards change in refractive index of the analyte. Here the analyte used is a solution of blood cells from an infected body and a healthy body. So, by comparing the change in refractive index of both the analytes, sensitivity of the proposed sensors are determined. Fibers are simulated by the Finite element method (FEM) in COMSOL Multiphysics Software. Black Phosphorous is used as a plasmonic material along with gold and Titanium Dioxide, that significantly increases the sensitivity of the proposed sensors. Cancer infected cells refractive ranges from 1.38 to 1.41 in refractive index and that healthy cells ranges from 1.36 to 1.39 .This high sensitivity values at such minute change in refractive index displays the potential of the sensors. All the required fabrication process are suggested to show the possibility of making such sensors for real world applications.