UNVEILING THE SWELLING, DRUG RELEASE, AND STRUCTURAL PROPERTIES OF HYDROGELS: UNDERSTANDING KINETICS FOR ADVANCED APPLICATIONS

Abstract

This review provides a thorough examination of hydrogels, versatile materials capable of absorbing and retaining large amounts of water. It covers their classification, synthesis, properties, and applications in various scientific fields such as biomedicine and environmental science. Hydrogels, defined as networks that swell when exposed to water but maintain their structure, possess biomimetic qualities like flexibility, softness, and compatibility with biological systems, making them ideal for uses like drug delivery and tissue engineering. The document discusses their classification based on natural or synthetic origins, detailing the distinct compositions and properties of each type. It also explains synthesis methods, including physical and chemical cross-linking techniques, and emphasizes the importance of understanding drug release kinetics for designing effective drug delivery systems. The increasing focus on hydrogel-based systems, particularly in drug delivery, is highlighted, indicating their growing recognition and potential across scientific fields. Compiled from various research articles and references, this review serves as a valuable resource for researchers, scientists, and enthusiasts interested in exploring hydrogel science further.