NUGEN: DATABASE OF RARE AND COMMON GENETIC VARIATIONS OF GENES RELATED TO NUTRITION

Abstract

Food is one of the basic requirement for human being. However, it does not mean that whatever human intake is good for it individually. Every human being have different genetic makeup, hence it react differently with different nutrients and this reaction may or may not increase the risk of a disease. The relationship between the human genome and nutritional factors has led to the development of new field called nutrigenomics. In addition, this work is the extension to the field. For the diagnoses and better treatment decisions of various disease, it is necessary to gather information about it. As the data about the diseases caused by various food factors and genes related to nutritional diseases is scattered across a large number of electronic publications, several specialized databases and other repositories. Moreover, nutrigenomics is a new field hence the data is quite difficult to find.

Thus, my objective was to create an efficient, effective and accurate system to enable the extraction of the detailed information related to polymorphism, phenotype, function and relationship between various population and allele frequencies of genes causing nutritional disorder by contributing resources from various databases. It helps to maintain the research and biomedical community by providing a comprehensive repository of information related to genes causing diseases found through text mining.