ABSORPTION AND EMISSION STUDIES ON THE INTERACTION OF RIBOFLAVIN WITH SYNTHETIC POLYMERS

Abstract

Protein-protein interactions and drug-protein interactions are an important field in medical sciences. The impact and strength of the drug-protein interactions play significant role in the biological activity of the drugs. The non-covalent association between the drug and protein molecules always provides stability to the drug action. In a similar way, the interaction between the drug and its carrier molecules are also plays important role in the efficient delivery and action of the drug molecules. The polymers are promising molecules due to their surface, bulk and improved pharmacokinetic properties. In the present work, we have tried to study the interaction between polymer and riboflavin to understand their stability under different micro environment. The polymers like poly(methyl methacrylate) (PMMA), poly(ethylene glycol) (PEG) and poly(vinyl alcohol) (PVA) have been utilized as biomedical materials due to their biocompatibility and polar nature.