NEUROLOGICAL CHANNELOPATHIC KNOWLEDGE BASE (NCKB):AN APPLICATION SOFTWARE FOR LON CHANNELS AND NEUROLOGICAL CHANNELOPATHIES

Abstract

Biological databases are the central repositories where important experimental information is stored. Raw data is useless until or unless it is backed up by a good database management system. RDBMS has the capability of deriving implicit meaning out of raw facts. In modern biology, databases turned their faces towards the development in the field of bioinformatics. Now a day databases are being lodged with the data analysis tool where that data be a DNA sequence, protein sequence or protein structure. Data is meaningless with the absence of its analytic tools in bioinformatics. Structured query language is a potent non procedural language which is very well being used for the database creation. Such a platform is provided by Microsoft in form of MS SQL Server. Moreover interactive user interface is also an interesting criterion for the database development. Today database have spread their arms in every field of biology. Till date in field of neuroscience various databases are accessible which is having information regarding gene expression, neurons, macroscopic brain structure, and neurological or psychiatric disorders. But still there is no database repository for neurological channelopathies. Neurological Channelopathic Knowledge Base (NCKB) will provide detailed pathological information about the neurological channelopathies as well as detailed information about the ion channels involved in the neurological disorders. This database has been integrated with online bioinformatical tools. Herein we have developed i) Neurological Channelopathic Knowledge Base- a software with complete package of Neurological channelopedia, Neurological channelopathies database and interactive data retrieval user interface.