http://dspace.dtu.ac.in:8080/jspui/handle/123456789/107 2026-04-28T05:26:09Z http://dspace.dtu.ac.in:8080/jspui/handle/repository/15362 Title: USE OF ECOFRIENDLY IN LOW TEMPERATURE CIRCUIT IN TERMS OF FIRST LAW AND SECOND LAW EFFICIENCY OF THREE STAGES CASCADE REFRIGERATION OF BIOMEDICAL APPLICATIONS Authors: MISHRA, R.S. Abstract: Biomedical preservation requires storing biological specimens like stem cells blood and organs, at a storage temperature below -95oC, Hence, the main aim of the current research is to conduct a thermodynamic energy and exergy analysis to determine the thermal performance of three stages cascade refrigeration systems in the high temperature condenser temperature using R1234ze and R1234yf in high temperature circuit of condenser temperature of 70oC and zero degree centrigade of first evaporator temperature in High temperature circuit, and evaporator temperature(-80oC) in intermediate circuit using R134a and R410a as ecofriendly refrigerants is investigated. For low temperature evaporator temperature (-135oC) using hydrocarbons (R290, R600 and R600a), R404aand other refrigerants in low temperature evaporator circuit on system performances (i.e. overall system coefficient of performance, (first law efficiency), exergetic efficiency (second law efficiency) and system exergy destruction ratio (EDR) is investigated in three stages /four stages cascade refrigeration systems are shown in this paper. 2015-01-01T00:00:00Z